Loss of tissue non-specific alkaline phosphatase (TNAP) enzyme activity in cerebral microvessels is coupled to persistent neuroinflammation and behavioral deficits in late sepsis
To read more please click on the link below. Read Article
Tissue-Nonspecific Alkaline Phosphatase—A Gatekeeper of Physiological Conditions in Health and a Modulator of Biological Environments in Disease
To read more please click on the link below. Read Article
Pharmacokinetics of Asfotase Alfa in Adult Patients With Pediatric‐Onset Hypophosphatasia
To read more please click on the link below. Read Article
Rare genetic variants affecting urine metabolite levels link population variation to inborn errors of metabolism
To read more please click on the link below. Read Article
Endocrine Diseases of Newborn: Epidemiology, Pathogenesis, Therapeutic Options, and Outcome “Current Insights Into Disorders of Calcium and Phosphate in the Newborn”
To read more please click on the link below. Read Article
Looking for new anabolic treatment from rare diseases of bone formation
To read more please click on the link below. Read Article
A Patient’s Guide to Navigating the Insurance Appeals Process
Please download and view this fact sheet with the link below. Download Fact Sheet
Diagnosis of Hypophosphatasia in Adults Presenting with Metatarsal Stress Fracture: Proof‐of‐Concept for a Case Finding Strategy
To read more please click on the link below. Read Article
Investigation of ALPL variant states and clinical outcomes: An analysis of adults and adolescents with hypophosphatasia treated with asfotase alfa
To read more please click on the link below. Read Article
Spring 2021 Newsletter
To view the Newsletter please click the link below. View the Spring 2021 Newsletter