Scientific Publications

Scientific Publications

Alkaline Phosphatase: Placental and Tissue-nonspecific lsoenzymes Hydrolyze Phosphoethanolamine, Inorganic Pyrophosphate, and Pyridoxal 5′-Phosphate Substrate Accumulation in Carriers of Hypophosphatasia Corrects during Pregnancy

To read more please click on the link below. Read...

Key Learnings from Clinical Research and Real World Evidence on Asfotase Alfa Effectiveness in Hypophosphatasia10 Years Post-Approval

To read more please click on the link below. Read...

Medical Management of Hypophosphatasia: Review of Data on Asfotase Alfa (March, 2025) Kathryn McCrystal Dahir and Nancy S. Dunbar

To read more please click on the link below. Read...

Whole genome sequencing in adults with clinical hallmarks of hypophosphatasia negative for ALPL variants

To read more please click on the link below. Read...

Safety, pharmacokinetics, and pharmacodynamics of efzimfotase alfa, a second-generation enzyme replacement therapy: phase 1, dose-escalation study in adults with hypophosphatasia

To read more please click on the link below. Read...

Prevalence of chondrocalcinosis and calcium pyrophosphate deposition disease in a cohort of adult patients with low alkaline phosphatase levels and a positive versus negative genetic ALPL study

To read more please click on the link below. Read...

Gene Therapy for Hypophosphatasia: Current Management and Future

To read more please click on the link below. Read...

Circulating Micro-RNAs in Patients with Hypophosphatasia Results of the first micro-RNA analysis in HPP

To read more please click on the link below. Read...

Enzyme replacement therapy for hypophosphatasia — The current paradigm

To read more please click on the link below. Read...

First reported magnesium pyrophosphate kidney stone prompts diagnosis of hypophosphatasia

To read more please click on the link below. Read...

Mail Address (P.O Box)
The US Hypophosphatasia Foundation
141 Hawkins Place, #267
Boonton, NJ 07005, USA.

Organization

Programs

Community

Office Address (Location for meetings and events)
1719 NJ-10, Suite 315
Parsippany, NJ 07054

Follow Us on Social Media!

Disclaimer: This Website is owned by Soft Bones, Inc. All materials contained in this Website (the “Materials”) are either owned by or licensed to us and are protected by intellectual property and other laws. We retain all proprietary rights to the Materials. This Website is copyrighted. All rights are reserved. Except as expressly authorized by us, any use, copy, reproduction, display, performance, modification or retransmission of the Materials is strictly prohibited.